biotectonichome roundtranp
Schiller Lab


ecoli_images
kolben scaffold
resi_gum
TBLM
hcp1&hedgehog


      Chemical Biology                                          BioNanotechnology                                      Chemical Biology
whitearrow transp down

Home
Research Schiller Group People Stefan M. Schiller Publications
Presentations Media/Press Lectures
Funding
News
Contact



                    
                                              
Welcome to the Schiller Lab



Chemical Biology & Synthetic BioNanotechnology

The focus of our research can be described as bionic chemistry.
We take molecular concepts from natural systems and redesign its molecules and functions via a novel approach combining the power of synthetic organic and macromolecular chemistry with synthetic biology and bionanotechnology to ask and answer challenging questions in chemistry, material science, biology and medicine.


Our concepts are applied in analyzing and controlling intracellular networks, especially via genetically encoded protein switches and unnatural amino acids the latter allowing to define posttranlational modifications.
The development and understanding of new catalytic systems in their dynamic range based on, or mimiking enzyme functions (e.g. for green polymer chemistry, renewable materials and biofuel).
Biomimetic platforms for dynamic epitope presentation, the biosynthesis of defined structural and functional molecular building blocks (molecular tectons) e.g. based on elastine like proteins (ELPs) in regenerative medicine as dynamic extracellular matrix systems serving as stem cell niche, as template in biomineralization and as an example for a protein based rubber material and last but not least donut shaped proteins in nanobiotechnology for example as defined biolabeling platforms utilizing quantum dots, molecular electronics and biological solar cells.
Finally rational design of defined protein tectons allows for the in vitro and in vivo self-assembly of higher order structures such as e.g. nanocages or artificial compartments designated as potential reaction chambers for novel biosynthetic pathways.

                  
 TEM stack

 


backarrow upZBSA banner
All information offered on this site are copyrighted. Distribution via internet or other media is prohibited.  All rights reserved.
Document made with KompoZer
Revised Dez. 2014 by M. C. Huber Impressum